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The establishment of the FDA, or the Food and Drug Administration, occurred in the early 20th century, specifically through the Pure Food and Drug Act of 1906. This legislation aimed to regulate food and drugs to ensure the safety and efficacy of these products for consumers. Hence, the era during which the FDA was established is typically referred to as the Historical era, as it marks significant developments in the regulation of food and pharmaceuticals in the context of increasing consumer protection and public health awareness.

In this Historical era, various social reforms aimed at improving the quality of life and standards of living were being enacted, leading to the formation of numerous regulatory bodies. The subsequent choices, such as the New Deal or the Great Society, refer to later periods characterized by distinct legislative efforts and policies initiated during the 1930s and the 1960s respectively, which focused more on economic recovery and social welfare rather than the foundational regulations concerning food and drug safety established during the earlier Historical era.